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Low-dose radiation therapy (LDRT) for COVID-19 and its deadlier variants
Arch Toxicol. 2021 Jul 24:1-8. doi: 10.1007/s00204-021-03124-x. Online ahead of print.ABSTRACTCoronavirus variants are gaining strongholds throughout the globe. Despite early signals that SARS-CoV-2 coronavirus case numbers are easing up in the United States and during the middle of a (not so easy) vaccination roll out, the country has passed a grim landmark of 600,000 deaths. We contend that these numbers would have been much lower if the medical community undertook serious investigations into the potential of low doses of radiation (LDRT) as a mainstream treatment modality for COVID-19 pneumonia. LDRT has been posited to...
Source: Archives of Toxicology - July 24, 2021 Category: Toxicology Authors: Rachna Kapoor James S Welsh Vikas Dhawan Seyed Alireza Javadinia Edward J Calabrese Gaurav Dhawan Source Type: research

The Theoretical Value of Whole-Lung Irradiation for COVID-19 Pneumonia: A Reasonable and Safe Solution until Targeted Treatments are Developed
Radiat Res. 2021 Mar 16. doi: 10.1667/RADE-20-00261.1. Online ahead of print.ABSTRACTIn this work, we considered the theoretical role of low-dose radiation therapy (approximately 0.5-1.0 Gy) in the treatment of respiratory distress syndrome associated with COVID-19 infection. Monte Carlo calculations were performed to gauge the ability to deliver low-dose radiation to the thoracic mid-plane using an orthovoltage machine. In addition, the potential harm of a single dose of 0.75 Gy (whole-lung irradiation) was assessed based on the recommendations of the BEIR-VII committee of the U.S. National Research Council. Based on the ...
Source: Radiation Research - March 16, 2021 Category: Physics Authors: Viacheslav Soyfer Yehoshua Socol Dimitri Bragilovski Benjamin W Corn Source Type: research